Rebecca L Gould, Christopher J McDermott, Benjamin J Thompson, Charlotte V Rawlinson, Matt Bursnall, Mike Bradburn, Pavithra Kumar, Emily J Turton, David A White, Marc A Serfaty, Christopher D Graham, Lance M McCracken, Laura H Goldstein, Ammar Al-Chalabi, Richard W Orrell, Tim Williams, Rupert Noad, Idris Baker, Christina Faull, Thomas Lambert, Suresh K Chhetri, John Ealing, Anthony Hanratty, Aleksandar Radunovic, Nushan Gunawardana, Gail Meadows, George H Gorrie, Tracey Young, Vanessa Lawrence, Cindy Cooper, Pamela J Shaw, Robert J Howard
BACKGROUND: Motor neuron disease is a progressive, fatal neurodegenerative disease for which there is no cure. Acceptance and Commitment Therapy (ACT) is a psychological therapy incorporating acceptance, mindfulness, and behaviour change techniques. We aimed to evaluate the effectiveness of ACT plus usual care, compared with usual care alone, for improving quality of life in people with motor neuron disease. METHODS: We conducted a parallel, multicentre, two-arm randomised controlled trial in 16 UK motor neuron disease care centres or clinics...
May 9, 2024: Lancet