Shaofan Lin, Ming Gao, Zehong Yang, Ruihuan Yu, Zhuozhi Dai, Chuling Jiang, Yubin Yao, Tingting Xu, Jiali Chen, Kainan Huang, Daiying Lin
Background: CT is increasingly detecting thyroid nodules. Prior studies indicated a potential role of CT-based radiomics models in characterizing thyroid nodules, although lacked external validation. Objectives: To develop and validate a CT-based radiomics model for the differentiation of benign and malignant thyroid nodules. Methods: This retrospective study included 378 patients (mean age, 46.3±13.9 years; 86 men, 292 women) with 408 resected thyroid nodules (145 benign, 263 malignant) from two centers (center 1: 293 nodules, January 2018-December 2022; center 2: 115 nodules, January 2020-December 2022), who underwent preoperative multiphase neck CT (noncontrast, arterial, and venous phases)...
May 1, 2024: AJR. American Journal of Roentgenology