Anais Codorniu, Emilie Charbit, Marie Werner, Arthur James, Jean-Luc Hanouz, Daniel Jost, Armelle Severin, Elodie Lang, Julien Pottecher, Malory Favreau, Emmanuel Weiss, Paer Selim Abback, Jean-Denis Moyer
BACKGROUND AND IMPORTANCE: Occurrence of mydriasis during the prehospital management of traumatic brain injury (TBI) may suggest severe intracranial hypertension (ICH) subsequent to brain herniation. The initiation of hyperosmolar therapy to reduce ICH and brain herniation is recommended. Whether mannitol or hypertonic saline solution (HSS) should be preferred is unknown. OBJECTIVES: The objective of this study is to assess whether HSS, compared with mannitol, is associated with improved survival in adult trauma patients with TBI and mydriasis...
April 30, 2024: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine